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I've come across the term "prime medicine" in recent discussions regarding healthcare advancements, but I'm still somewhat perplexed about its exact purpose and function. Could you elaborate on what prime medicine entails? Specifically, I'm curious about its core principles, potential applications, and how it differs from traditional medical practices. Are there any particular areas where prime medicine has shown significant promise or advancements? Additionally, I'd like to know if there are any challenges or limitations associated with this approach to healthcare. Your insights would be greatly appreciated.